Epidemiology and Pathophysiology of Benign Thyroid Disease
نویسنده
چکیده
Epidemiology Goiter: In iodine-deficient areas, goiter prevalence may be as high as 80%. After correction of iodine deficiency, prevalence decreases slowly over a generation’s time to but not below a few per cent. In iodine-sufficient areas, cross-sectional studies showed a decline in frequency of diffuse goiter and, in contrast, an increase of thyroid nodules and thyroid antibodies with age. For prevalence of diffuse goiter, the ratio of women to men is at least 4:1. Hyperthyroidism: In iodine-sufficient areas, Graves’ disease is the most frequent cause of hyperthyroidism and accounts for about 70% of the cases. Its prevalence may be as high as 1%. In areas with actual or recent iodine deficiency, Plummer’s disease is more frequent due to a much higher prevalence of nodular goiter. Prevalence and incidence of thyrotoxicosis is higher in females than in males by a factor of 5 to 10.
منابع مشابه
Incidental thyroid uptake during 99mTc-methylene diphosphonate bone scintigraphy in oncologic patients
Introduction: Extraosseous accumulation of 99mTc – methylene diphosphonate (MDP) may be due to neoplastic, dystrophic, hormonal, inflammatory, ischemic, traumatic or excretory disorders. 99mTc-MDP incidental thyroid uptake is not frequent and is possibly caused by the presence of dystrophic or metastatic calcification, biopsy procedure and presence of beni...
متن کاملبررسی ده ساله 420 مورد تیروئید کتومی در بیمارستان شهید دکتر رهنمون
This is a retrospective study of 420 patients undergone thyroidectomy in Rahnemoon hospital during last 10 years. The results are as follows: Thyroid malignancies and surgical procedures were three times more common in female than male. Mean age was 38.2 years for male and 35.1 for female. For both sex 4th decade of life was the most common age of disease. 22% of patients had Positive family hi...
متن کاملEpidemiology of Goiter and Benign Tumors of the Thyroid Gland in Albania
AIM The aim of this study was to describe the demographic characteristics and disease patterns among patients with thyroid nodular abnormalities (goiter) and benign tumors of the thyroid gland in Albania, a transitional country in South Eastern Europe. METHODS Our study included all patients diagnosed with goiter and/or benign tumors of the thyroid gland who were hospitalized at the Universit...
متن کاملChanges in salivary gland function following radioiodine therapy of thyroid diseases: A comparison of high-dose therapy for thyroid cancer and low-dose therapy for benign thyroid disease
Introduction: High-dose radioactive iodine therapy in differentiated thyroid cancer (DTC) may adversely affect the salivary gland function. This study is aimed to evaluate the effect of radioactive iodine (RAI) with dose of 100 mCi in DTC patients compared to lower doses of less than 30 mCi in hyperthyroid cases. Methods: Fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...
متن کاملNonradiation risk factors for thyroid cancer in the US Radiologic Technologists Study.
The incidence of thyroid cancer has been rapidly increasing in the United States, but few risk factors have been established. The authors prospectively examined the associations of self-reported medical history, anthropometric factors, and behavioral factors with thyroid cancer risk among 90,713 US radiologic technologists (69,506 women and 21,207 men) followed from 1983 through 2006. Incident ...
متن کامل